SigmatoeOS: reasoning and execution, separated by design
An agentic operating system that dynamically constructs and runs R&D pipelines — from a research question to an auditable finding, and on to executable wet lab protocols.
A mesh of specialized agents, working in parallel
The Scout Mesh decomposes a research question into specialized sub-agents that run analyses simultaneously, then converge on a single, auditable finding.
Docking Scout
Runs structure-based docking across ligand libraries and ranks binding poses.
ADMET Scout
Predicts absorption, distribution, metabolism, excretion, and toxicity profiles.
Literature Scout
Synthesizes prior art and evidence with citations traced to source.
Assay Design Scout
Proposes and validates assay parameters ready for wet lab execution.
Five layers that separate reasoning from execution
Every action is deterministic and verifiable — by design, not by convention.
Audit & Compliance
A cryptographically secure audit trail records every decision and action for regulatory review.
Orchestration
Dynamically constructs and runs R&D pipelines, decomposing questions into parallel work.
Agent Fabric
The Scout Mesh of specialized autonomous agents that reason, plan, and converge on findings.
Tool & Data Integration
Connects to cheminformatics, dry lab pipelines, and your existing scientific data sources.
Wet Lab Interface
Translates experimental designs into executable protocols for automation instruments.
Plugs into your existing scientific stack
An Embed SDK connects Sigmatoe directly into the tools your team already lives in — like Benchling and Jupyter — so scouts can pull data and hand back results without any manual glue code.
Cheminformatics
- RDKit
- AlphaFold 3
- OpenBabel
- DataWarrior
Dry Lab Pipelines
- BLAST+
- Schrödinger Suite
- Jupyter
- Nextflow
Wet Lab Automation
- Hamilton STAR
- Tecan Fluent
- Opentrons
- Cellario
Data & Notebooks
- Benchling
- Hamilton Venus
- LabArchives
- Private Cloud
Built for regulated industries
Enterprise-grade controls so you can adopt autonomous R&D with confidence.
21 CFR Part 11 Ready
Cryptographically secure, tamper-evident audit trail for every action.
SOC 2 In Progress
Controls and monitoring aligned to SOC 2 Type II standards.
HIPAA Aligned
Safeguards for handling protected and sensitive research data.
On-Premise Deployment
Deploy fully within your own private cloud or on-premise environment — your data never leaves your control.
Bring autonomy to your R&D pipeline
Join the teams moving from hypothesis to discovery in hours. Request access and we'll build a deployment plan for your lab.